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    RuBi-Gaba

  • Biological Activity

    Ruthenium-bipyridine-triphenylphosphine caged GABA that is excited by visible wavelengths and has two-photon uncaging capabilities. Provides greater tissue penetration, less phototoxicity, faster photorelease kinetics and better spatial resolution than UV light-sensitive caged compounds. Produces GABA receptor-mediated currents in pyramidal neurons in vitro and displays no effect on endogenous GABAergic or glutamatergic transmission at concentrations effective for uncaging.

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